Hospital IVF room

IVF room

IVF (In Vitro Fertilization) is a special clinic for obstetrics, hormonal and reproductive specialists. They are used to perform artificial insemination techniques. IVF rooms provide a stable and sterile environment to create the best conditions for insemination.


IVF room in hospital

The IVF room is a highly technical, demanding IVF room, and it is one of the most demanding rooms in the hospital. To build a standard IVF room, it is necessary to consider the environmental factors that must be controlled to ensure that the in vitro fertilization process has the highest success rate.

IVF room requirements

The environmental requirements in the IVF room are stringent.

  • Requirements for cleanliness demand for cleanliness
  • Heat and humidity requirements
  • Requirements for air pressure
  • Light requirements
  • Microbiological requirements

Standards in construction in the IVF

To achieve a high success rate, ensure the quality of the environment in the IVF room. We need to adhere to strict air standards in the IVF room. Currently, when designing an IVF room, it is necessary to meet the requirements for cleanliness according to GMP-WHO, GMP-EU as follows:

  • Lab – IVF, Buffer room, embryo, and oocyte storage room: Class 1000 (ISO 6);
  • Clean Storage, TESE Operating Room, Ovulation Room: Class 10,000 (ISO 7);
  • Clean Corridor Area: Class 100,000 (ISO 8);

The IVF laboratory is an important factor contributing to 70% of IVF success. Therefore, the construction of the IVF room must ensure the quality and stability of the IVF Lab, including air quality such as dust and volatile compounds (VOCs) affecting the quality of embryo culture. Currently, high-performance HEPA filters are the standard method to remove dust in the laboratory. However, HEPA filters only remove dirt and microorganisms but cannot filter impurities in the air, especially volatile organic compounds (VOCs).

A qualified IVF room needs to meet the following standards


VOCs (Volatile Organic Compounds) are volatile organic compounds that cause air pollution. In the IVF room, VOCs can affect the quality of the inoculum and the fertilization process’s success rate.

  • VOCs >1 ppm có thể trực tiếp gây độc cho phổi
  • Between 0.5 ppm and one ppm: Allows the development of the blastocyst and fetus; however, the miscarriage rate is still high.
  • From 0 ppm to 0.2 ppm: This is the best rate to get pregnant.

(ppm: Parts per million)

Temperature and humidity

The temperature in the IVF room should be in the range of 20-25 degrees Celsius. The air humidity should be between 40-60%.

Noise level

The noise level in the IVF room complies with international environmental safety and quality standards. The noise level in the IVF room is allowed in the range of 50 -70 dB(A)

To achieve this, the equipment in the IVF room needs to be designed to operate with low noise or housed in a warmly insulated enclosure. Along with that, the design must take measures to minimize noise in the HVAC system.

  • Wrap the sound absorption layer in the air duct from the AHU with materials such as glass cloth, mineral wool, vulcanized rubber, …
  • Soundproofing the machine room where the AHU is located to minimize the noise level caused by the equipment
  • AHU machine room soundproofing system includes a sound-absorbing hemp foam layer and silver-white glass hemp fabric.

The light

  • Lighting: White LEDs should be used to avoid affecting the embryo culture process.
  • Light intensity: Light intensity should be kept low, in the range of 300-500 lux, to ensure the stability of the workpiece.
  • Lighting time: Lighting time in the IVF room should be reduced to about 12-16 hours/day to limit the influence of light on the embryo.
  • Red and blue light: Red and blue light should be avoided in the IVF room because it can affect embryo development.

Vi sinh

To ensure the air quality in the areas according to the cleanliness levels in the IVF room, it is necessary to implement methods to control the microbiological level in the operating state, such as air sampling, agar plate placement, and surface sampling—Face, etc. This is very important because the IVF room requires high standards. Therefore, when building an IVF room, the investor should choose an experienced and highly specialized unit to achieve the best results.

The reason why the IVF room is not up to standard

The operating room needs to comply with many requirements to ensure a high level of cleanliness. However, many factors can cause air pollution in the operating room, including corridors connecting operating rooms, medical staff not following hygiene instructions, partially open doors, and maintenance and repair work. Filter replacement is not specified enough.

In addition, the difficulty of monitoring airborne particle concentrations can lead to inability to determine when to replace filters or determine whether a room is up to a clean standard.

HVAC systems and hallways are also natural breeding grounds for microorganisms, which can spread disease, so decontamination should be done regularly to reduce the risk.

ivf room in hospital

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